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If you need to be on a GLP-1 medication long-term, the disruption of cycling between medications may undermine the stability that long-term treatment requires

Avoid skipping meals even though appetite is reducedthis practice maintains steady glucose levels and prevents fatigue from becoming more severe

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These protective effects have been consistently observed across various animal and cell models

More specifically, it may interact with N-methyl-D-aspartate (NMDA) receptors, gamma-aminobutyric acid (GABA) receptors, and alpha 1-adrenergic receptors in the central nervous system [1, 2]